Top 50 Supplement Trends in 2026 (Backed by data)

Rachid Idali

by Rachid Idali

Below you'll find the top 50 supplement trends for 2026, spotted by Rising Trends's trend radar algorithm.

These topics were detected from online sources including TikTok, X (Twitter), Instagram, Reddit, news outlets, and Google Search data. Each trend has at least 1,000+ monthly searches and over 20% year-over-year growth.

Top 50 Fastest-Growing Supplement Trends

All supplement trends with over 20% year-over-year growth, ranked by search growth rate.

1

Magnesium Glycinate

823K vol+22%
2

L-theanine

301K vol+50%
3

Probiotic Gut Health

201K vol13.6x
4

Spirulina

201K vol+22%
5

Psyllium Husk

165K vol+22%
6

Fenbendazole

110K vol+49%
7

Oregano Oil

90.5K vol+22%
8

Magnesium L-threonate

74K vol+22%
9

Berberine Supplement

74K vol+49%
10

Multivitamin For Women

74K vol2.7x
11

Rhodiola Rosea

60.5K vol2.7x
12

Methylene Blue Benefits

60.5K vol4.1x
13

Propolis

60.5K vol+22%
14

Electrolyte Drink Mix

60.5K vol20.9x
15

Iodine Supplement

60.5K vol+22%
16

Creatine Gummies

60.5K vol+49%
17

Dandelion Root

49.5K vol2.2x
18

Creatine For Women

49.5K vol2.2x
19

Omega 3 Fatty Acids

49.5K vol+22%
20

Gut Health Supplement

40.5K vol3.4x
21

Liposomal Glutathione

40.5K vol+22%
22

Boric Acid Vaginal Suppositories

40.5K vol+49%
23

Glp-1 Supplements

33.1K vol+22%
24

Vitamin D3 K2

33.1K vol+22%
25

High-protein Shakes

33.1K vol5.0x
26

Palo Azul

27.1K vol+22%
27

Glutathione Supplement

22.2K vol2.2x
28

Clear Protein Powder

22.2K vol3.4x
29

Moringa Supplement

22.2K vol2.2x
30

Black Cumin Seed Oil

22.2K vol+50%
31

Beet Root Powder Benefits

18.1K vol+22%
32

Natural Health Supplements

18.1K vol69.6x
33

Sleep Supplements

18.1K vol2.7x
34

The Natural Healing Handbook

14.8K vol1480x
35

Magnesium Glycinate Gummies

14.8K vol+49%
36

Spike Protein Detox

14.8K vol7.8x
37

Beef Organ Supplement

14.8K vol+22%
38

Women's Health Supplements

12.1K vol13.8x
39

Rhodiola Rosea Benefits

12.1K vol+83%
40

Hydrolyzed Collagen Peptides

12.1K vol+22%
41

Myo Inositol Supplement

12.1K vol2.8x
42

Bovine Colostrum Supplement

12.1K vol9.3x
43

Sparkling Protein Water

9.9K vol7.6x
44

Vaginal Probiotic Gummies

9.9K vol11.3x
45

Dandelion Root Extract

9.9K vol4.1x
46

Nattokinase Supplement

9.9K vol+83%
47

Beet Root Supplement

9.9K vol+83%
48

Mood Magic

9.9K vol38.1x
49

Saffron For Adhd

9.9K vol3.4x
50

Bone Broth Powder

8.1K vol+50%

Showing top 10 of 50 supplement trends

The Supplement Industry: 2026's Hottest Segments

Segment Market Size Growth Notable Brands
Mineral Supplements ~$15.8B ~7.2% CAGR Thorne, Pure Encapsulations
Cognitive & Adaptogens ~$8.2B ~12.4% CAGR Momentous, Four Sigmatic
Gut Health & Probiotics ~$65B ~9.1% CAGR Seed, Athletic Greens
Sports & Protein ~$52B ~8.5% CAGR Optimum Nutrition, LMNT
Longevity & Anti-aging ~$4.5B ~14.8% CAGR ProHealth, DoNotAge
Herbal & Botanical ~$32B ~6.8% CAGR Gaia Herbs, Nature's Way

CAGR = compound annual growth rate

For insights into how we track these consumer shifts, read our deep-dive on Google Trends for market research to understand the data behind these findings.


1. Mineral Supplements

The minerals category has become the cornerstone of modern supplementation. "Magnesium glycinate" dominates with 823,000 monthly searches and +22% year-over-year growth, while "magnesium l-threonate" attracts 74,000 searches as people seek brain-specific benefits. Even iodine is resurging with 60,500 monthly searches.

Magnesium Glycinate

823KVolume
10x5Y
0300K600K899K11/2011/2111/2211/2311/2410/25

Magnesium L-threonate

74KVolume
+814%5Y
033K66K99K11/2011/2111/2211/2311/2410/25

What was once a basic multivitamin afterthought has evolved into a precision nutrition category, with consumers choosing specific mineral forms for targeted outcomes.

Behind the Mineral Renaissance

This category is exploding because:

  • Form-specific education: Consumers learned that glycinate, threonate, and citrate forms have different absorption rates and benefits
  • Deficiency awareness: Soil depletion and processed foods have created widespread mineral deficiencies – up to 68% of Americans are magnesium deficient
  • Sleep connection: Magnesium glycinate's calming effects have made it the #1 natural sleep supplement
  • Cognitive health: Magnesium l-threonate is the only form clinically shown to raise brain magnesium levels
  • Thyroid concerns: Iodine interest has surged as people connect it to metabolic function and energy

The mineral supplements market is projected to reach $15.8 billion by 2028, with specialized forms commanding significant premiums over generic oxide formulations.

What's Gaining Momentum

Magnesium Glycinate (823,000 searches, +22% YoY) – The preferred form for sleep and relaxation. Glycine itself is a calming neurotransmitter, creating a synergistic effect. Thorne and Pure Encapsulations lead in quality.

Magnesium L-Threonate (74,000 searches, +22% YoY) – Developed at MIT, this patented form (Magtein) is the only one proven to significantly increase brain magnesium. Used for memory, learning, and cognitive aging.

Iodine Supplement (60,500 searches, +22% YoY) – Essential for thyroid function, iodine deficiency has become more common as people reduce salt intake. Nascent iodine and potassium iodide are the most popular forms.

Vitamin D3 K2 (33,100 searches, +22% YoY) – The combination that ensures calcium goes to bones, not arteries. K2 activates proteins that direct calcium metabolism – without it, D3 supplementation may be incomplete.

Notable Companies

  • Thorne – Trusted by Olympic athletes and healthcare practitioners
  • Pure Encapsulations – Hypoallergenic formulas without fillers
  • Life Extension – Research-backed formulations with clinical dosing
  • LMNT – Made electrolyte supplementation mainstream with their sodium-focused formula

2. Cognitive Performance & Adaptogens

Brain optimization has gone mainstream. "L-theanine" generates 301,000 monthly searches with +50% growth, "rhodiola rosea" is up +173% with 60,500 searches, and "methylene blue benefits" has surged +309% as biohackers explore pharmaceutical-grade cognitive enhancement.

L-theanine

301KVolume
+123%5Y
76K212K348K484K10/2010/2110/2210/2310/2409/25

Rhodiola Rosea

61KVolume
+400%5Y
7K27K46K65K11/2011/2111/2211/2311/2410/25

The nootropics and adaptogens space has evolved from fringe biohacking to evidence-based cognitive support that professionals rely on daily.

The Cognitive Enhancement Wave

This category is surging because:

  • Work performance pressure: Knowledge workers seek any edge in focus, memory, and mental stamina
  • Caffeine alternatives: L-theanine provides calm focus without jitters – often stacked with coffee
  • Stress epidemic: Adaptogens like rhodiola help the body resist chronic stress, the #1 cognitive impairment cause
  • Research validation: Double-blind studies on rhodiola, ashwagandha, and lion's mane have legitimized adaptogens
  • Mitochondrial biohacking: Methylene blue's effects on cellular energy production have captured the longevity community

The cognitive supplements market is expected to exceed $8.2 billion by 2027, with adaptogens being the fastest-growing subcategory.

What's Gaining Momentum

L-Theanine (301,000 searches, +50% YoY) – Found in green tea, this amino acid promotes alpha brain waves associated with relaxed alertness. The 100mg L-theanine + coffee stack has become a productivity staple.

Rhodiola Rosea (60,500 searches, +173% YoY) – An Arctic adaptogen used by Russian athletes and cosmonauts. Clinical trials show improved mental performance under stress and reduced fatigue. Nootropics Depot offers standardized extracts.

Methylene Blue Benefits (60,500 searches, +309% YoY) – Originally a century-old medication, low-dose methylene blue enhances mitochondrial function and has neuroprotective properties. Used by longevity enthusiasts and those with cognitive concerns.

Stress Relief Supplements (6,600 searches, +175% YoY) – Comprehensive formulas combining multiple adaptogens (ashwagandha, rhodiola, holy basil) for HPA axis support. Moon Juice's SuperYou popularized this category.

Notable Companies

  • Momentous – NSF-certified supplements used by professional athletes and military
  • Nootropics Depot – Rigorous third-party testing on cognitive enhancers
  • Four Sigmatic – Made functional mushrooms accessible with coffee blends
  • Moon Juice – Premium adaptogens for the wellness-conscious consumer

3. Gut Health Revolution

The gut microbiome has captured consumer attention like never before. "Probiotic gut health" commands 201,000 monthly searches with an extraordinary +1,258% year-over-year growth, while "gut health supplement" is up +235% and "psyllium husk" maintains 165,000 monthly searches.

Probiotic Gut Health

201KVolume
68x5Y
0110K221K331K10/2010/2110/2210/2310/2409/25

Gut Health Supplement

41KVolume
10x5Y
015K29K44K11/2011/2111/2211/2311/2410/25

Science has validated what consumers intuited: gut health impacts everything from immunity to mood to skin clarity.

Why Gut Health Dominates

The gut health category is exploding because:

  • Gut-brain axis awareness: Research showing gut bacteria produce 90% of serotonin has connected digestion to mental health
  • Autoimmune connections: Leaky gut and dysbiosis are now linked to inflammatory conditions from acne to arthritis
  • Probiotic strain specificity: Consumers learned that different strains (Lactobacillus, Bifidobacterium, Saccharomyces) have different benefits
  • Fiber deficit crisis: Average American fiber intake is 15g/day – half the recommended amount, driving prebiotic interest
  • Post-antibiotic recovery: The need to rebuild gut flora after antibiotics has created a massive market

The global probiotics market is projected to reach $65 billion by 2027, with innovative delivery systems and strain-specific products driving growth.

What's Gaining Momentum

Probiotic Gut Health (201,000 searches, +1,258% YoY) – The fastest-growing health search term in our database. Consumers want targeted probiotic formulas rather than generic yogurt cultures. Seed's DS-01 has set a new standard for efficacy.

Psyllium Husk (165,000 searches, +22% YoY) – Soluble fiber that feeds beneficial bacteria and promotes regularity. Unlike harsh laxatives, psyllium gently bulks stool and supports a healthy microbiome.

Gut Health Supplement (40,500 searches, +235% YoY) – Comprehensive formulas combining probiotics, prebiotics, and digestive enzymes. Athletic Greens AG1 has made daily gut support routine.

Akkermansia Benefits (2,900 searches, +53% YoY) – The emerging star of next-generation probiotics. This keystone species is associated with metabolic health and has been nearly impossible to supplement – until recently.

Notable Companies

  • Seed – Science-first probiotic with 24 clinically-studied strains in a dual-capsule delivery system
  • Athletic Greens – Made "greens powders" mainstream with their all-in-one formula
  • Pendulum – First company to offer live Akkermansia muciniphila in a probiotic
  • Viome – Personalized probiotics based on individual microbiome testing

4. Sports Nutrition & Protein

Performance nutrition continues its massive expansion. "Creatine" dominates with 550,000 monthly searches, "electrolyte drink mix" has surged +1,986% with 60,500 searches, and "creatine for women" is up +123% as the compound sheds its male-only stigma.

Creatine

550KVolume
+124%5Y
188K419K650K881K10/2010/2110/2210/2310/2409/25

Creatine For Women

50KVolume
16x5Y
027K54K81K11/2011/2111/2211/2311/2410/25

Athletes and everyday fitness enthusiasts are adopting sports nutrition principles, driven by social media education and accessible products.

The Mainstream Sports Nutrition Shift

Sports nutrition is booming because:

  • Creatine cognitive benefits: Beyond muscle, creatine supports brain energy – leading women and non-athletes to adopt it
  • Sodium rehabilitation: After decades of demonization, sodium's role in hydration and performance is being recognized
  • Clean protein demand: The protein powder lead contamination scandal (246K searches) pushed consumers toward tested brands
  • Female fitness growth: Women's participation in strength training has exploded, creating demand for female-focused formulations
  • Convenience formats: Gummies, drink mixes, and ready-to-drink options have eliminated friction

The sports nutrition market is expected to reach $52 billion by 2028, with electrolytes and creatine showing the strongest momentum.

What's Gaining Momentum

Creatine (550,000 searches) – The most researched supplement in existence. Originally for bodybuilders, creatine is now used for brain health, aging, and women's wellness. Creatine monohydrate remains the gold standard.

Electrolyte Drink Mix (60,500 searches, +1,986% YoY) – The standout trend of 2026. LMNT and Liquid IV have transformed hydration from sports drinks to functional wellness.

Creatine for Women (49,500 searches, +123% YoY) – Women are discovering creatine's benefits for strength, bone health, and cognitive function. Brands are creating smaller serving sizes and female-focused marketing.

Creatine Gummies (60,500 searches, +49% YoY) – The gummy format has made creatine more palatable and convenient. Perfect for those who dislike powder mixtures.

Notable Companies

  • LMNT – Electrolyte brand that educated consumers on sodium's importance, no sugar
  • Optimum Nutrition – Gold standard whey protein with decades of trust
  • Momentous – Premium creatine and protein used by professional sports teams
  • Transparent Labs – Third-party tested sports nutrition with no artificial ingredients

5. Longevity & Anti-aging Compounds

The pursuit of healthspan is driving interest in cutting-edge compounds. "Berberine supplement" has 74,000 monthly searches with +49% growth, "NMN supplement" maintains 60,500 searches despite regulatory challenges, and "fenbendazole" has gained 110,000 searches as an unconventional intervention.

Berberine Supplement

74KVolume
13x5Y
074K147K221K10/2010/2110/2210/2310/2409/25

Nmn Supplement

61KVolume
+400%5Y
033K66K100K11/2011/2111/2211/2311/2410/25

Consumers are no longer satisfied with simply not being sick – they want to optimize cellular health and extend their healthy years.

The Longevity Movement

Anti-aging supplements are surging because:

  • Metabolic health focus: Berberine's effects on blood sugar rival prescription metformin, with fewer side effects
  • NAD+ science: Research on declining NAD+ levels with age has popularized precursors like NMN and NR
  • Rapamycin awareness: mTOR inhibition research has spillover effects on natural alternatives like berberine
  • Biohacking community: Podcasters like Peter Attia and David Sinclair have made longevity science accessible
  • Off-label exploration: Desperation for anti-aging solutions drives interest in veterinary drugs and research chemicals

The longevity supplements market is projected to grow at 14.8% CAGR, making it the fastest-growing supplement category.

What's Gaining Momentum

Berberine Supplement (74,000 searches, +49% YoY) – Called "nature's Ozempic" for its blood sugar and weight management effects. The bright yellow compound activates AMPK, a master metabolic switch. Often combined with Ceylon cinnamon.

NMN Supplement (60,500 searches) – Nicotinamide mononucleotide is a direct NAD+ precursor. Despite FDA regulatory scrutiny, demand remains strong. ProHealth and DoNotAge lead the market.

Glutathione Supplement (22,200 searches, +124% YoY) – The "master antioxidant" that declines with age. Liposomal delivery has made oral supplementation viable; previously only IV glutathione was effective.

Nattokinase Supplement (9,900 searches, +83% YoY) – A Japanese fermented soy enzyme that supports healthy circulation and fibrinolytic activity. Interest spiked with cardiovascular health concerns.

Notable Companies

  • ProHealth Longevity – Pioneered NMN supplementation with pharmaceutical-grade purity
  • DoNotAge – UK-based longevity brand with a cult following for their NMN and rapamycin alternatives
  • Life Extension – Research foundation with decades of anti-aging supplement expertise
  • Elysium Health – Founded by MIT scientists, offers NAD+ precursor Basis

6. Herbal & Botanical Extracts

Traditional herbs are experiencing modern validation. "Dandelion root" commands 49,500 searches with +123% growth, "moringa supplement" has 22,200 searches at +124%, and "oregano oil" maintains 90,500 monthly searches for its antimicrobial properties.

Dandelion Root

50KVolume
+173%5Y
10K29K47K65K11/2011/2111/2211/2311/2410/25

Moringa Supplement

22KVolume
+825%5Y
027K54K81K11/2011/2111/2211/2311/2410/25

Ancient remedies are being rediscovered through the lens of modern pharmacology, creating a bridge between traditional medicine and evidence-based supplementation.

The Botanical Renaissance

Herbal supplements are thriving because:

  • Detox and cleansing culture: Dandelion root's liver-supportive properties align with cleansing trends
  • Superfood expansion: Moringa's nutrient density (92 nutrients, 46 antioxidants) earned it "miracle tree" status
  • Antimicrobial resistance: As antibiotic resistance grows, natural antimicrobials like oregano oil gain interest
  • Whole-plant philosophy: Consumers prefer botanical complexity over isolated synthetic compounds
  • Sustainable sourcing: Herbal products often have better environmental profiles than synthetic alternatives

The herbal supplements market is valued at $32 billion and growing at 6.8% annually, with liver support and adaptogenic herbs leading growth.

What's Gaining Momentum

Dandelion Root (49,500 searches, +123% YoY) – Used for centuries as a liver tonic, modern research confirms its hepatoprotective and mild diuretic effects. Popular as tea, tincture, or capsules.

Moringa Supplement (22,200 searches, +124% YoY) – Called "the drumstick tree" in India, moringa leaves contain exceptional protein for a plant (25%) plus iron, calcium, and all essential amino acids. Kuli Kuli leads in Western markets.

Oregano Oil (90,500 searches, +22% YoY) – Potent antimicrobial from carvacrol and thymol compounds. Used for immune support, gut health, and as a natural alternative to antibiotics for minor infections.

Propolis (60,500 searches, +22% YoY) – Bee-produced resin with over 300 bioactive compounds. Used for immune support, oral health, and wound healing. Beekeeper's Naturals made it mainstream.

Notable Companies

  • Gaia Herbs – Certified organic herbs with seed-to-shelf traceability
  • Nature's Way – Legacy botanical brand with extensive quality testing
  • Beekeeper's Naturals – Modern bee products with clean formulations
  • Herb Pharm – Liquid herbal extracts made from sustainably wildcrafted and organic herbs

Summary

The supplement landscape in 2026 reveals a sophisticated consumer who has moved far beyond basic multivitamins. Whether they're optimizing with magnesium glycinate (823K monthly searches), enhancing cognition with L-theanine (+50% growth), rebuilding their gut with probiotics (+1,258% growth), or pursuing longevity with berberine (+49% growth) – today's supplement buyer demands evidence, quality, and targeted solutions.

The winning brands in this market share key characteristics:

  • Third-party testing that verifies purity and potency claims
  • Form-specific innovation matching the right compound form to desired outcomes
  • Educational marketing that explains mechanisms, not just benefits
  • Transparent sourcing showing ingredient origins and manufacturing standards

For entrepreneurs and investors, the data points to several high-growth opportunities: specialized mineral forms, clinically-dosed adaptogens, next-generation probiotics with specific strains, clean sports nutrition for women, and longevity compounds with emerging research support.

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Written By

Rachid Idali

Founder of Rising Trends, helping entrepreneurs identify and capitalize on emerging market opportunities through expert trend analysis and insights.